王晨飞，博士生导师，同济大学生命科学与技术学院生物信息系长聘教授，梧桐岛生命科学研究院客座研究员。研究方向为生物信息学与人工智能，微环境与疾病发生。近年来发展了一系列单细胞时空多组学数据增强、生成和功能解析智能算法，揭示了复杂微环境中多细胞协作与疾病发生的关联机制。以通讯作者（含共同）身份在Nat. Genet.、Nat. Cancer. 、Cell Stem Cell、Genome Biol.、Nucleic Acids Res.等杂志发表二十余篇论文。担任Nat. Rev. Genet.、Nat. Methods、Nat. Cell Biol.、Genome Biol., Nat. Commun.等杂志审稿人，BMC Bioinfor.杂志编委。主持和参与多个国家级科研项目，包括科技部重点研发青年项目、国家优青、面上、青年基金等。获得吴瑞奖学金、博新计划、上海市科技启明星等荣誉。担任上海市生物信息学会理事，青年委员会主任委员。
王晨飞
客座研究员
致力于 计算生物学, AI, 单细胞组学, 系统免疫学, 基因表达调控
国家优青
吴瑞奖学金
学术简介
代表性成果
2025
Reference-guided computational framework identifies microenvironment metabolic subtypes and targets using pan-cancer single-cell datasets
Ke Tang, Ya Han, Dongqing Sun, Xin Dong, Tong Han, Hailin Wei, Wenwen Shao, Junjie Hu, Zhaoyang Liu, Lele Zhang, Taiwen Li, Peng Zhang, Qiu Wu, Chenfei Wang
Genome Medicine
DOI
2025
Cisformer: a scalable cross-modality generation framework for decoding transcriptional regulation at single-cell resolution
Luzhang Ji, Qihang Zou, Ke Tang, Chenfei Wang
Genome Biology
DOI
2025
Spatiotemporal analyses of the pan-cancer single-cell landscape reveal widespread profibrotic ecotypes associated with tumor immunity
Ya Han, Lele Zhang, Dongqing Sun, Guangxu Cao, Yuting Wang, Jiali Yue, Junjie Hu, Zhonghua Dong, Fang Li, Taiwen Li, Peng Zhang, Qiu Wu, Chenfei Wang
Nature Cancer
DOI
2025
Multi-omic profiling highlights factors associated with resistance to immuno-chemotherapy in non-small-cell lung cancer
Yilv Yan, Dongqing Sun, Junjie Hu, Yue Chen, Liangdong Sun, Huansha Yu, Yicheng Xiong, Zhida Huang, Haoran Xia, Xinsheng Zhu, Dongliang Bian, Fenghuan Sun, Likun Hou, Chunyan Wu, Orion R. Fan, Haiyang Hu, An Zeng, Lele Zhang, Yi Eve Sun, Chenfei Wang, Peng Zhang
Nature Genetics
DOI
2023
Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang
Cancer Immunology Research
DOI
2022
Single-cell gene regulation network inference by large-scale data integration
Xin Dong, Ke Tang, Yunfan Xu, Hailin Wei, Tong Han, Chenfei Wang
Nucleic Acids Research
DOI
2022
Evaluation of cell-cell interaction methods by integrating single-cell RNA sequencing data with spatial information
Zhaoyang Liu, Dongqing Sun, Chenfei Wang
Genome Biology
DOI
2022
STRIDE: accurately decomposing and integrating spatial transcriptomics using single-cell RNA sequencing
Dongqing Sun, Zhaoyang Liu, Taiwen Li, Qiu Wu, Chenfei Wang
Nucleic Acids Research
DOI
2021
TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment
Dongqing Sun, Jin Wang, Ya Han, Xin Dong, Jun Ge, Rongbin Zheng, Xiaoying Shi, Binbin Wang, Ziyi Li, Pengfei Ren, Liangdong Sun, Yilv Yan, Peng Zhang, Fan Zhang, Taiwen Li, Chenfei Wang
Nucleic Acids Research
DOI