张云芳，同济大学生命科学与技术学院教授、博士生导师，国家优青、同济大学附属妇产科医院双聘教授、上海市梧桐岛生命科学研究院客座研究员。研究主要非编码RNA及RNA修饰介导的表观调控机制，相关研究成果以第一及通讯作者在Science、Nat Cell Biol、Nat Rev Endocrinol等杂志发表论文近30篇，他引2000余次。研究成果曾入选“中国科学十大进展”及“全国妇幼健康科学技术奖自然科学奖一等奖”等。主持国家自然科学基金优青项目、面上项目、国家科技部重点研发计划课题等基金；个人曾获吴瑞奖、中国科学院院长特别奖等。现任中国细胞生物学学会生殖细胞生物学分会常务委员、中国动物学会生殖生物学分会委员、中国优生科学协会生殖遗传与胚胎学分会委员、同济大学科学技术协会委员会委员，并担任《Noncoding RNA Research》和《Genes & Diseases》杂志副主编。
学术简介
代表性成果
2025
Optimized identification and characterization of small RNAs with PANDORA-seq
Junchao Shi, Yunfang Zhang, Yun Li, Liwen Zhang, Xudong Zhang, Menghong Yan, Qi Chen, Ying Zhang
Nature Protocols
DOI
2021
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications
Junchao Shi, Yunfang Zhang, Dongmei Tan, Xudong Zhang, Menghong Yan, Ying Zhang, Reuben Franklin, Marta Shahbazi, Kirsty Mackinlay, Shichao Liu, Bernhard Kuhle, Emma R. James, Liwen Zhang, Yongcun Qu, Qiwei Zhai, Wenxin Zhao, Linlin Zhao, Changcheng Zhou, Weifeng Gu, Jernej Murn, Jingtao Guo, Douglas T. Carrell, Yinsheng Wang, Xuemei Chen, Bradley R. Cairns, Xiang-lei Yang, Paul Schimmel, Magdalena Zernicka-Goetz, Sihem Cheloufi, Ying Zhang, Tong Zhou, Qi Chen
Nature Cell Biology
DOI
2018
Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs
Yunfang Zhang, Xudong Zhang, Junchao Shi, Francesca Tuorto, Xin Li, Yusheng Liu, Reinhard Liebers, Liwen Zhang, Yongcun Qu, Jingjing Qian, Maya Pahima, Ying Liu, Menghong Yan, Zhonghong Cao, Xiaohua Lei, Yujing Cao, Hongying Peng, Shichao Liu, Yue Wang, Huili Zheng, Rebekah Woolsey, David Quilici, Qiwei Zhai, Lei Li, Tong Zhou, Wei Yan, Frank Lyko, Ying Zhang, Qi Zhou, Enkui Duan, Qi Chen
Nature Cell Biology
DOI
2016
Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder
Qi Chen, Menghong Yan, Zhonghong Cao, Xin Li, Yunfang Zhang, Junchao Shi, Gui-hai Feng, Hongying Peng, Xudong Zhang, Ying Zhang, Jingjing Qian, Enkui Duan, Qiwei Zhai, Qi Zhou
Science
DOI