The Zhu Lab

Investigating Large Animal Cell Lineage Development, Livestock Breeding, Large Animal Model

PI Profile

Research

Large Animal Cell Lineage Development, Livestock Breeding, Large Animal Model

Our Team

Jiang Zhu
Principal Investigator

Publications

2024
Pivotal role for long noncoding RNAs in zygotic genome activation in mice
Kang Chen, Wenju Liu, Jiang Zhu, Xiaochen Kou, Yanhong Zhao, Hong Wang, Cizhong Jiang, Shaorong Gao, Lan Kang
Science China Life Sciences DOI
2023
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei
Jiang Zhu, Kang Chen, Yu H. Sun, Wen Ye, Juntao Liu, Dandan Zhang, Nan Su, Li Wu, Xiaochen Kou, Yanhong Zhao, Hong Wang, Shaorong Gao, Lan Kang
Nature Communications DOI
2021
Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs
Yu H. Sun, Ruoqiao Huiyi Wang, Khai Du, Jiang Zhu, Jihong Zheng, Li Huitong Xie, Amanda A. Pereira, Chao Zhang, Emiliano P. Ricci, Xin Zhiguo Li
Nature Communications DOI
2020
Ribosomes guide pachytene piRNA formation on long intergenic piRNA precursors
Yu H. Sun, Jiang Zhu, Li Huitong Xie, Ziwei Li, Rajyalakshmi Meduri, Xiaopeng Zhu, Chi Song, Chen Chen, Emiliano P. Ricci, Zhiping Weng, Xin Zhiguo Li
Nature Cell Biology DOI
2017
Corticotrophin-releasing hormone and corticosterone impair development of preimplantation embryos by inducing oviductal cell apoptosis via activating the Fas system: an in vitro study
Xiu-Wen Tan, Chang-Li Ji, Liang-Liang Zheng, Jie Zhang, Hong-Jie Yuan, Shuai Gong, Jiang Zhu, Jing-He Tan
Human Reproduction DOI
2017
Expression profiles and function analysis of microRNAs in postovulatory aging mouse oocytes
Tian-Yang Wang, Jie Zhang, Jiang Zhu, Hua-Yu Lian, Hong-Jie Yuan, Min Gao, Ming-Jiu Luo, Jing-He Tan
Aging DOI
2017
CDX2 is essential for cell proliferation and polarity in porcine blastocysts
Gerelchimeg Bou, Shichao Liu, Mingju Sun, Jiang Zhu, Binghua Xue, Jia Guo, Yueming Zhao, Bo Qu, Xiaogang Weng, Yanchang Wei, Lei Lei, Zhonghua Liu
Development DOI
2016
The relationship between apoptosis, chromatin configuration, histone modification and competence of oocytes: A study using the mouse ovary-holding stress model
Juan Lin, Fei Chen, Ming-Ju Sun, Jiang Zhu, You-Wei Li, Liu-Zhu Pan, Jie Zhang, Jing-He Tan
Scientific Reports DOI
2016
The relationship between apoptosis, chromatin configuration, histone modification and competence of oocytes: A study using the mouse ovary-holding stress model
Juan Lin, Fei Chen, Ming-Ju Sun, Jiang Zhu, You-Wei Li, Liu-Zhu Pan, Jie Zhang, Jing-He Tan
Scientific Reports DOI
2016
Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos
Yan Jun HUAN, Zhan Feng WU, Ji Guang ZHANG, Jiang ZHU, Bing Teng XIE, Jian Yu WANG, Jing Yu LI, Bing Hua XUE, Qing Ran KONG, Zhong Hua LIU
Journal of Reproduction and Development DOI
2016
The signaling pathways by which the Fas/FasL system accelerates oocyte aging
Jiang Zhu, Fei-Hu Lin, Jie Zhang, Juan Lin, Hong Li, You-Wei Li, Xiu-Wen Tan, Jing-He Tan
Aging DOI
2015
Ovulation Statuses of Surrogate Gilts Are Associated with the Efficiency of Excellent Pig Cloning
Yanjun Huan, Kui Hu, Bingteng Xie, Yongqian Shi, Feng Wang, Yang Zhou, Shichao Liu, Bo Huang, Jiang Zhu, Zhongfeng Liu, Yilong He, Jingyu Li, Qingran Kong, Zhonghua Liu
PLOS ONE DOI
2015
Epigenetic Modification Agents Improve Gene-Specific Methylation Reprogramming in Porcine Cloned Embryos
Yanjun Huan, Zhanfeng Wu, Jiguang Zhang, Jiang Zhu, Zhonghua Liu, Xuexiong Song
PLOS ONE DOI
2015
Epigenetic Modification of Cloned Embryos Improves Nanog Reprogramming in Pigs
Yanjun Huan, Hongmei Wang, Zhanfeng Wu, Jiguang Zhang, Jiang Zhu, Zhonghua Liu, Hongbin He
Cellular Reprogramming DOI
2015
Trichostatin A Rescues the Disrupted Imprinting Induced by Somatic Cell Nuclear Transfer in Pigs
Yanjun Huan, Jiang Zhu, Bo Huang, Yanshuang Mu, Qingran Kong, Zhonghua Liu
PLOS ONE DOI
2015
Cumulus cells accelerate oocyte aging by releasing soluble Fas Ligand in mice
Jiang Zhu, Jie Zhang, Hong Li, Tian-Yang Wang, Chuan-Xin Zhang, Ming-Jiu Luo, Jing-He Tan
Scientific Reports DOI
2014
A pre-breeding screening program for transgenic boars based on fluorescence in situ hybridization assay
Gerelchimeg Bou, Mingju Sun, Ming Lv, Jiang Zhu, Hui Li, Juan Wang, Lu Li, Zhongfeng Liu, Zhong Zheng, Wenteng He, Qingran Kong, Zhonghua Liu
Transgenic Research DOI
2014
Role of Na+/Ca2+ Exchanger (NCX) in Modulating Postovulatory Aging of Mouse and Rat Oocytes
Chuan-Xin Zhang, Wei Cui, Min Zhang, Jie Zhang, Tian-Yang Wang, Jiang Zhu, Guang-Zhong Jiao, Jing-He Tan
PLoS ONE DOI
2014
Non-frozen preservation protocols for mature mouse oocytes dramatically extend their developmental competence by reducing oxidative stress
T.-Y. Wang, Q. Li, Q. Li, H. Li, J. Zhu, W. Cui, G.-Z. Jiao, J.-H. Tan
Molecular Human Reproduction DOI
2014
Epigenetic Modification Agents Improve Genomic Methylation Reprogramming in Porcine Cloned Embryos
Yan Jun HUAN, Jiang ZHU, Hong Mei WANG, Zhan Feng WU, Ji Guang ZHANG, Bing Teng XIE, Jing Yu LI, Qing Ran KONG, Zhong Hua LIU, Hong Bin HE
Journal of Reproduction and Development DOI
2013
Treating Cloned Embryos, But Not Donor Cells, with 5-aza-2’-deoxycytidine Enhances the Developmental Competence of Porcine Cloned Embryos
Yan Jun HUAN, Jiang ZHU, Bing Teng XIE, Jian Yu WANG, Shi Chao LIU, Yang ZHOU, Qing Ran KONG, Hong Bin HE, Zhong Hua LIU
Journal of Reproduction and Development DOI
2011
Overexpression Nanog Activates Pluripotent Genes in Porcine Fetal Fibroblasts and Nuclear Transfer Embryos
Li Zhang, Yi‐Bo Luo, Gerelchimeg Bou, Qing‐Ran Kong, Yan‐Jun Huan, Jiang Zhu, Jian‐Yu Wang, Hui Li, Feng Wang, Yong‐Qian Shi, Yan‐Chang Wei, Zhong‐Hua Liu
The Anatomical Record DOI
2011
TSA improve transgenic porcine cloned embryo development and transgene expression
Qing-Ran KONG, Jiang ZHU, Bo HUANG, Yan-Jun HUAN, Feng WANG, Yong-Qian SHI, Zhong-Feng LIU, Mei-Ling WU, Zhong-Hua LIU
Hereditas (Beijing) DOI
2010
Aberrant Expression and Methylation Status of Putatively Imprinted Genes in Placenta of Cloned Piglets
Yanchang Wei, Jiang Zhu, Yanjun Huan, Zhongfeng Liu, Cairong Yang, Xinmiao Zhang, Yanshuang Mu, Ping Xia, Zhouhua Liu
Cellular Reprogramming DOI
Contact
朱江 Lab
Sycamore Research Institute of Life Sciences

No. 88 Zhangjiang Road, Pudong New Area
Shanghai, China